Ageing: Gene variant found in centenarians may be linked to longer lifespan

A rare variant of the SIRT6 gene increases DNA repair in human cells, and learning its effects could help to develop anti-ageing drugs Health 31 January 2022 By Michael Le Page A cake for a 100th birthday kajakiki/Getty Images A rare gene variant identified in people who have lived to 100 or more appears to … Read more

Wolves Already Had The Genetic Mutation to Turn Into Tiny Dogs 54,000 Years Ago

One of the main genetic mutations responsible for small size in certain dog breeds, such as Pomeranians and Chihuahuas, evolved in dog relatives long before humans began breeding these miniature companions. Researchers discovered that the mutation can even be traced back to wolves that lived more than 50,000 years ago.   Researchers discovered the mutation, which is found in … Read more

New dangers? Computers uncover 100,000 novel viruses in old genetic data | Science

It took just one virus to cripple the world’s economy and kill millions of people; yet virologists estimate that trillions of still-unknown viruses exist, many of which might be lethal or have the potential to spark the next pandemic. Now, they have a new—and very long—list of possible suspects to interrogate. By sifting through unprecedented … Read more

Scientists Identify Specific Gene Variant That Protects Against Severe COVID-19

Researchers have discovered a protective gene variant that seems to shield people from severe cases of COVID-19, and the finding could lead to new breakthroughs in fighting the coronavirus.   Since much earlier in the pandemic, scientists have been busily investigating how patient genetics influence the severity of a SARS-CoV-2 infection, exposing the inherited factors … Read more

New Evidence Challenges The Idea That Mutations Are Entirely Random

It’s a common misconception that evolution has a sense of direction – a notion that biology nerds around the world are constantly trying to correct. But new research reveals there may be a semblance of truth to this misconception, at least more than we ever realized.   While it’s not as straightforward as mutation with … Read more

mRNA technology: Vaccine biotech has helped repair broken hearts in mice

By Michael Le Page An illustration of a strand of mRNA MattLphotography / Alamy Stock Photo Immune cells in the bodies of mice have been temporarily reprogrammed to repair damaged hearts by removing scar tissue, thanks to the technology used in the mRNA coronavirus vaccines. “After you give the treatment, the scar goes away,” says … Read more

Genetic Therapies for Brain Diseases

Susan was still a child when she first suspected something might be wrong with her mother. A cup or plate would often crash to the floor by accident when her mother was serving dinner or washing up dishes. “She was, she would have said, ‘clumsy’, but she wasn’t really clumsy,” says Susan. “Her hands had … Read more

How a genetic twist in an ‘old’ variant may be driving Omicron and Delta today | Science

The new Omicron variant of the pandemic coronavirus has provided an avalanche of mutations, many never seen before, for scientists to ponder. And as with earlier variants, Omicron researchers are focused on numerous changes to the spike protein, which studs the surface of SARS-CoV-2 and allows it to latch on to and invade human cells. … Read more

Science of wine: European grapes have their genetic routes in western Asia

We used to think that European wine grapes were cultivated locally, independently of grape domestication in western Asia, but grape genetics suggests otherwise Humans 21 December 2021 By Carissa Wong Red grapes ready to be harvested in a vineyard alika/Shutterstock Grapes used to make common European wines may have originated from grapevines that were first … Read more