A Common Link Between Several Neurodegenerative Diseases Might Finally Be Identified

There’s a hallmark of incurable neurodegenerative diseases – misfolded proteins that clump together to form sticky plaques or tangles called fibrils. Now, new research has discovered that a protein normally tasked with clearing cells of molecular debris might be a common feature of a cluster of common and rare neurodegenerative diseases, including two distinct forms … Read more

New class of killer T cells may prevent autoimmune diseases | Science

The price for a vigilant immune system that can pounce on tumor cells or pathogens is occasional friendly fire—an autoimmune attack. Scientists have now identified a new type of human T cell that quells assaults on healthy tissues, a finding that could suggest treatments for conditions as diverse as lupus and cancer. “It’s a major … Read more

A Single Genetic Test Can Accurately Diagnose 25 Rare Diseases Faster Than Ever

Scientists have developed a quick genetic test that can diagnose a large range of rare muscle and nerve diseases with near perfect accuracy. Tandem repeat disorders are a family of over 50 inherited diseases, including Huntington’s disease and amyotrophic lateral sclerosis (ALS), that seem to occur when short DNA sequences are repeated too many times. … Read more

Wastewater Monitoring Offers Powerful Tool for Tracking COVID and Other Diseases

In 2020 experts at the U.S. Biomedical Advanced Research and Development Authority (BARDA) and other public health agencies watched a presentation that many thought was impractical at the time. Several companies proposed to regularly sample wastewater from sewers and treatment plants and run tests to detect SARS-CoV-2—the virus that causes COVID-19. People excrete the virus … Read more

2022 news preview: mRNA tech behind covid-19 vaccines could get new uses

By Michael Le Page A BioNTech worker tests the procedures for making mRNA Abdulhamid Hosbas/Anadolu Agency via Getty Images 2022 could be the year when we find out whether mRNA vaccine technology can be used for a lot more than just making vaccines. The hope is that it can also get our bodies to produce drugs that … Read more

Genetic Therapies for Brain Diseases

Susan was still a child when she first suspected something might be wrong with her mother. A cup or plate would often crash to the floor by accident when her mother was serving dinner or washing up dishes. “She was, she would have said, ‘clumsy’, but she wasn’t really clumsy,” says Susan. “Her hands had … Read more

There’s Something About Eating Mushrooms That Seems to Lower Depression Risk

A large-scale analysis of people who eat mushrooms suggests they have a lower risk of developing depression. The association is still a mystery, and for now, the authors say the data should be interpreted with caution. There’s always a chance the results are a mere correlation, especially since eating more mushrooms didn’t seem to lower … Read more

After COVID-19 Successes, Researchers Push to Develop mRNA Vaccines for Other Diseases

When the broad range of vaccines against COVID-19 were being tested in clinical trials, only a few experts expected the unproven technology of mRNA to be the star. Within 10 months, mRNA vaccines were both the first to be approved and the most effective. Although these are the first mRNA vaccines to be approved, the … Read more