Glowing tumor marker may interfere with cancer studies in mice, creating reproducibility problems | Science

Cancer biologist Cyrus Ghajar was gearing up to study how the immune system can fight breast cancer when he hit a snag: The supposedly fast-spreading cancer cells he implanted in mice stayed put and sometimes even disappeared after about 11 days. Then postdoc Candice Grzelak identified the culprit: the green fluorescent protein (GFP) the researchers … Read more