Wound healing: Genetically engineered cheese bacteria may help chronic wounds to heal

Lactococcus lactis bacteria have been engineered to produce skin-healing proteins and could be useful for treating diabetic ulcers



Health



15 March 2022

Lactococcus lactis bacteria,coloured scanning electron micrograph (SEM). This lactic acid-producing bacteria is used in the production of cheese and other fermented products. Magnification: x2500 when printed at 10 centimetres wide.

Lactococcus lactis bacteria seen in a scanning electron microscope image

STEVE GSCHMEISSNER/SCIENCE PHOTO LIBRARY

Cheese-making bacteria have been engineered to produce skin repair proteins that promote rapid healing when applied to wounds in mice. A clinical trial is now under way to see if they can help to heal chronic wounds that can develop in people with diabetes.

About a quarter of people with diabetes end up with open wounds called ulcers that don’t heal because of poor circulation and other complications. In severe cases, the affected body part – usually a foot – must …