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Lactococcus lactis bacteria have been engineered to produce skin-healing proteins and could be useful for treating diabetic ulcers Health 15 March 2022 By Alice Klein Lactococcus lactis bacteria seen in a scanning electron microscope image STEVE GSCHMEISSNER/SCIENCE PHOTO LIBRARY Cheese-making bacteria have been engineered to produce skin repair proteins that promote rapid healing when applied … Read more
There’s a hallmark of incurable neurodegenerative diseases – misfolded proteins that clump together to form sticky plaques or tangles called fibrils. Now, new research has discovered that a protein normally tasked with clearing cells of molecular debris might be a common feature of a cluster of common and rare neurodegenerative diseases, including two distinct forms … Read more
Multiple factors play a role in complex diseases like COVID, and knowing what they are is important for predicting how different people will be affected. Early on in the pandemic, being older, overweight, or smoking were identified as increasing your risk of developing severe COVID. This then informed public health decisions – the elderly were … Read more
Cells are continually cranking out new proteins, but like car factories, they produce some lemons. A study of mice now suggests these defective proteins speed aging, bolstering an idea first proposed 60 years ago. The new paper “fills a critical gap” and “allows us to say that protein damage is an accelerant of aging,” says … Read more
The first team to disable a disease gene directly in a person through an infusion of the genome editor CRISPR reported yesterday that levels of the toxic protein made by the gene dropped as much as 93% for up to 1 year. The researchers hope the long-term reduction means patients in the clinical trial will … Read more
The outer coat of the antibiotic-resistant bacterium Clostridium difficile has a structure similar to chain mail that stops drugs and immune system cells from killing it Health 25 February 2022 By Carissa Wong The outer proteins of Clostridium difficile form a structure like chain mail Newcastle University A bacterium called Clostridium difficile is known as … Read more
In the last few years, the deeply frustrating medical area of chronic migraine prevention has been revolutionized thanks to the discovery that a protein called calcitonin gene-related peptide, or CGRP, plays a role in the condition. While several drugs containing antibodies that block or bind the protein have now entered the market and are helping … Read more
Ground squirrels spend the end of summer gorging on food, preparing for hibernation. They need to store a lot of energy as fat, which becomes their primary fuel source underground in their hibernation burrows all winter long. While hibernating, ground squirrels enter a state called torpor. Their metabolism drops to as low as just … Read more
The world now has a new COVID-19 vaccine in its arsenal, and at a fraction of the cost per dose. Two years into the COVID-19 pandemic, the world has seen over 314 million infections and over 5.5 million deaths worldwide. Approximately 60 percent of the world population has received at least one dose of a … Read more
The question of how life first sparked into existence on our planet is one we haven’t yet fully answered, but science is getting closer all the time – and a new study identifies the structures of the proteins that may well have made it happen. To begin with, the team behind the study decided … Read more