Arthritis drug reduces mortality in severe COVID-19, huge clinical trial finds | Science

Baricitinib, an oral drug that dampens an overactive immune system and is commonly used by people with rheumatoid arthritis, reduced hospitalized COVID-19 patients’ risk of dying by 13%, investigators of the world’s largest trial of coronavirus treatments announced today. Patients in the study also took other drugs, such as the steroid dexamethasone, that act on … Read more

First gene-editing treatment injected into the blood reduces toxic protein for up to 1 year | Science

The first team to disable a disease gene directly in a person through an infusion of the genome editor CRISPR reported yesterday that levels of the toxic protein made by the gene dropped as much as 93% for up to 1 year. The researchers hope the long-term reduction means patients in the clinical trial will … Read more