FDA pushes cancer trials to include more elderly people | Science

Older adults make up a hefty proportion of cancer patients but a much smaller slice of clinical trial participants—a long-standing and vexing problem the U.S. Food and Drug Administration (FDA) wants drug companies to tackle. The agency yesterday released recommendations urging companies to boost representation of people over 65 years old, and especially over 75. … Read more

DIY treatments and clinical trials – one person’s tale of long covid

By MB Caschetta Illustration of a receptor on the surface of a B cell binding to SARS-CoV-2, as part of the body’s immune response. Anatomic Groove/Science Photo Library On Body Politic’s covid-19 support group, which uses the app Slack, my username says it all. I am MBCaschetta_May2020. I caught covid-19 on 15 May 2020 and … Read more

There’s a Reason 90% of Drugs Fail Clinical Trials, And We Can Fix It

It takes 10 to 15 years and around US$1 billion to develop one successful drug. Despite these significant investments in time and money, 90 percent of drug candidates in clinical trials fail.   Whether because they don’t adequately treat the condition they’re meant to target or the side effects are too strong, many drug candidates … Read more

Endometriosis Drug Shows Promise in Preliminary Phase 3 Trial Results

A new drug with the potential to treat endometriosis-associated pain with very few side effects is getting closer to official approval. Endometriosis is a chronic inflammatory condition and the leading cause of pelvic pain worldwide. With no known cause or cure, many patients have run out of options and are living with chronic and unrelenting symptoms.   … Read more

It’s Clearer Than Ever – The Active Compound in Ecstasy Can Safely Assist PTSD Therapy

For people with post-traumatic stress disorder, recalling memories of physical or sexual assault, combat or disaster-related events can induce intense anxiety or panic attacks as well as debilitating flashbacks.   In the US, about seven percent of people suffer from PTSD and lose an average of about four working days each month as a result. … Read more